Healthcare Industry News:  BREG  


 News Release - April 24, 2006

Orthofix's BREG Division Launches e-PainCare(TM) Electronic Pain Management Pump

HUNTERSVILLE, N.C.--(HSMN NewsFeed)--April 24, 2006--Orthofix International N.V. (NASDAQ: OFIX ) announced today that its BREG subsidiary has launched its newest ambulatory infusion pump, e-PainCare.

BREG's e-PainCare programmable electronic infusion pump delivers local anesthetics to a post-operative wound site, allowing patients to stay one step ahead of the pain curve.

"This new pump is an important addition to our line of products that manage patients' post surgical pain," said Alan Milinazzo, group president and CEO of Orthofix. "The recent growth in the pain management market has been driven by increasing numbers of outpatient surgeries, and e-PainCare was designed to help reduce medical costs and benefit patients through earlier ambulation, shorter hospital stays, and accelerated recovery."

e-PainCare is BREG's first electronic pain infusion pump, and is the latest addition to the company's full line of patient-controlled local infusion pumps designed to meet a variety of needs.

About BREG, Inc.

Since 1989, BREG, Inc., a division of Orthofix International N.V. (NASDAQ: OFIX ), has pioneered premium orthopedic, reconstructive and postoperative products. With a solid commitment to customer-driven innovation, BREG has established itself as a leader in the industry by continually delivering world-class solutions that address the critical needs of its customers. Based in Vista, California, BREG's products are currently distributed through a worldwide network of more than 100 distributors in 36 countries. The company's extensive product offerings including postoperative pain management products, CPM devices, and a full range of soft goods and functional knee braces are designed to meet the changing needs of its customers worldwide. BREG also offers inventory management services and solutions to create overall practice management efficiencies for health care providers. For more information visit

About Orthofix International, N.V.

Orthofix International N.V., a global diversified orthopedic products company, offers a broad line of minimally invasive surgical, and non-surgical products for the spine, reconstruction, and trauma market sectors that address the lifelong bone-and-joint health needs of patients of all ages, helping them achieve a more active and mobile lifestyle. Orthofix's products are widely distributed around the world to orthopedic surgeons and patients via Orthofix's sales representatives and its subsidiaries, including BREG, Inc., and via partnerships with other leading orthopedic product companies, such as Medtronic Sofamor Danek and Kendall Healthcare. In addition, Orthofix is collaborating in R&D partnerships with leading medical institutions such as the Orthopedic Research and Education Foundation, the Cleveland Clinic Foundation, Innovative Spinal Technologies and the National Osteoporosis Institute. For more information about Orthofix, please visit

Forward-Looking Statements

This news release contains certain forward-looking statements under the Private Securities Litigation Reform Act of 1995. These forward-looking statements may include, but are not limited to, statements concerning the projections, financial condition, results of operations and businesses of Orthofix, and are based on management's current expectations and estimates and involve risks and uncertainties that could cause actual results or outcomes to differ materially from those contemplated by the forward-looking statements. Factors that could cause or contribute to such differences may include, but are not limited to, risks relating to the integration of the businesses of Orthofix and Breg, unanticipated expenditures, changing relationship with customers, suppliers and strategic partners, risks relating to the protection of intellectual property, changes to the reimbursement policies of third parties, changes to governmental regulation of medical devices, the impact of competitive products, changes to the competitive environment, the acceptance of new products in the market, conditions of the orthopedic industry and the economy and other factors described in the most recent report on Form 10-K and other periodic reports filed by Orthofix with the Securities and Exchange Commission.

Source: Orthofix International

Issuer of this News Release is solely responsible for its content.
Please address inquiries directly to the issuing company.

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