Healthcare Industry News:  continuous glucose monitor 

Devices Drug Delivery

 News Release - May 9, 2006

Sontra Medical Introduces Generation 2.0 SonoPrep(R) Skin Permeation Device

Rolls Out New and Improved Ultrasonic Skin Permeation Device

FRANKLIN, Mass., May 9 (HSMN NewsFeed) -- Sontra Medical Corporation (Nasdaq: SONT ) announced today that it has introduced its 2nd Generation SonoPrep® skin permeation device for continuous transdermal glucose monitoring and topical lidocaine delivery. The 2nd Generation SonoPrep device incorporates several new features suggested by current SonoPrep customers. It is more portable and ergonomically friendly with improved features to provide clinician ease of use and patient comfort. New to the 2nd Generation system is a digital display that monitors system and patient treatment status. Also new is a removable battery that allows customers to recharge backup batteries for heavy use conditions. "We are pleased to launch the new SonoPrep device following a rigorous process of design, development and validation," stated Scott Kellogg, V.P. of Research and Development. "Based on input we have received, we designed a more robust device that is simpler to use and less expensive to manufacture."

The SonoPrep ultrasonic skin permeation employs low frequency ultrasound to penetrate the skin's outermost layer, the stratum corneum. This simple and fast (average 15 second) treatment creates an imperceptible window through the skin that enables molecules to pass through with 100 times greater efficiency than intact skin. The SonoPrep ultrasonic skin permeation device makes the skin permeable for up to twenty four hours for continuous non invasive diagnostics such as glucose monitoring and transdermal drug delivery.

About Sontra Medical Corporation (

Sontra Medical Corporation is a technology leader in transdermal science. Sontra's SonoPrep ultrasound-mediated skin permeation technology combined with technical competencies in transdermal drug formulation, delivery systems and biosensors is creating a new paradigm in transdermal drug delivery and diagnosis. The SonoPrep technology is being developed for several billion dollar market opportunities, including continuous glucose monitoring and the transdermal delivery of large molecule drugs and vaccines. Sontra is currently marketing the SonoPrep device and procedure tray for use with topical lidocaine to achieve rapid (within five minutes) skin anesthesia.

Sean Moran, Sontra Medical CFO

SonoPrep is a registered trademark of Sontra Medical Corporation. All other company, product or service names mentioned herein are the trademarks or registered trademarks of their respective owners.

This press release contains forward-looking statements, which address a variety of subjects including, for example, the expected technological advances and availability of the second-generation SonoPrep device, the expected benefits and efficacy of the SonoPrep device in connection with diagnostics, vaccine delivery, glucose monitoring and transdermal drug delivery, Sontra's expected ability to develop, market and sell products based on its technology; the expected market opportunities, distribution and market acceptance of the SonoPrep device and technology, and Sontra's business, research, product development, regulatory approval, marketing and distribution plans and strategies. Statements that are not historical facts, including statements about our beliefs and expectations, are forward-looking statements. Such statements are based on our current expectations and are subject to a number of factors and uncertainties, which could cause actual results to differ materially from those described in the forward-looking statements. The following important factors and uncertainties, among others, could cause actual results to differ materially from those described in these forward-looking statements: our technology is new and we may experience adverse results in research and development efforts, product development, clinical trials, product evaluations, commercialization efforts, product distribution and market acceptance; markets for our products may develop slower than expected, or not at all; our sales cycle is lengthy and we are still developing sales and marketing strategies which may or may not prove effective; the SonoPrep device may not prove effective in connection with diagnostics, vaccine delivery, glucose monitoring and/or transdermal drug delivery; we may experience difficulties or delays in obtaining regulatory approvals to market products resulting from development efforts or difficulties or delays associated with sources of regulatory-approved transdermal drugs and vaccines; failure to obtain and maintain patent protection for discoveries or commercial limitations imposed by patents owned or controlled by third parties would have an adverse effect on us; we depend upon strategic partners and third-party distributors to develop, commercialize, market and sell products based on our work; and we require substantial additional funding to conduct research and development and to expand commercialization, distribution and marketing activities. For detailed information about factors that could cause actual results to differ materially from those described in the forward-looking statements, please refer to Sontra's filings with the Securities and Exchange Commission, including Sontra's most recent Quarterly Report on Form 10-QSB. Forward-looking statements represent management's current expectations and are inherently uncertain. We do not undertake any obligation to update forward-looking statements made by us.

Source: Sontra Medical

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