Healthcare Industry News:  RiVax 

Biopharmaceuticals Personnel

 News Release - May 17, 2006

Acambis announces forthcoming retirement of Chief Scientific Officer

Cambridge, UK and Cambridge, Massachusetts - 17 May 2006 - (HSMN NewsFeed) - Acambis plc ("Acambis") (LSE: ACM, NASDAQ: ACAM) announces that Dr Thomas Monath, 65, will retire as Chief Scientific Officer and Executive Director of Acambis at the Annual General Meeting on 23 June 2006. Dr Monath will then serve as a Non- Executive Director of Acambis until 1 September 2006 following which he will provide advice to Acambis from time to time on its smallpox and ChimeRiVax vaccines.

Dr Monath has been with Acambis and its predecessor companies for over 14 years. Having previously served as Vice President, Research and Medical Affairs, he was appointed Chief Scientific Officer and a member of the Board in March 2002. During that time, he has overseen the development of many of the products within Acambis' pipeline of vaccines.

Dr Monath said:

"My 14 years at Acambis have been some of the most rewarding of my career. During my time with the Company, Acambis has matured considerably and has an excellent management team at the Board, scientific and operational level. I am very proud of our achievement in delivering on the ACAM2000 US Government contract, for which the ACAM2000 Biologics License Application was recently submitted to the FDA, and that our pipeline has continued to advance so successfully. I will maintain strong links with the Company and have every confidence that the scientists and management team will continue to take the company from strength to strength."

Gordon Cameron, Chief Executive Officer of Acambis, said:

"We are indebted to Tom for spearheading the research programmes that have grown into the core of our development-stage pipeline. Although Tom is retiring from his full-time role, I am delighted that he will maintain his links with the Company and we look forward to continuing to benefit from his knowledge and experience through that relationship."

About Acambis

Acambis is a leading developer of vaccines to prevent and treat infectious diseases. Recognised internationally as the leading producer of smallpox vaccines, Acambis is developing an investigational smallpox vaccine, ACAM2000, and is manufacturing emergency-use stockpiles of this investigational vaccine for the US Government and other governments around the world. It is also developing an attenuated smallpox vaccine, MVA3000, under contracts with the US National Institutes of Health. Acambis' US-based subsidiary Berna Products Corporation markets Vivotif®, the world's only licensed oral typhoid vaccine, in North America. Acambis' investigational vaccine against Japanese encephalitis, ChimeRiVax-JE, is undergoing Phase 3 clinical testing. It also has the most advanced investigational vaccine against the West Nile virus, which has spread to 48 US States in the last seven years, and a vaccine against Clostridium difficile bacteria, a leading cause of hospital-acquired infections.

Acambis is based in Cambridge, UK and Cambridge, Massachusetts, US. Its primary listing is on the London Stock Exchange (ACM) and its shares are listed in the form of American Depositary Receipts on NASDAQ (ACAM). More information is available at

"Safe Harbor" statement under the Private Securities Litigation Reform Act of 1995:

The statements in this news release that are not historical facts are forward-looking statements that involve risks and uncertainties, including the timing and results of clinical trials, product development, manufacturing and commercialisation risks, the risks of satisfying the regulatory approval process in a timely manner, the need for and the availability of additional capital. For a discussion of these and other risks and uncertainties see "Risk management" in the Company's 2004 Annual Report and "Risk factors" in its Form 20-F, in addition to those detailed on the Company's website and in the Company's filings made with the Securities and Exchange Commission from time to time. These forward-looking statements are based on estimates and assumptions made by the management of Acambis and are believed to be reasonable, though are inherently uncertain and difficult to predict. Actual results or experience could differ materially from the forward-looking statements.

Source: Acambis

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