Healthcare Industry News:  TG100-115 

Biopharmaceuticals Cardiology FDA

 News Release - June 29, 2006

FDA Grants Fast Track Designation for TargeGen TG100-115 Cardiovascular Compound

SAN DIEGO, June 29 (HSMN NewsFeed) -- TargeGen, Inc., a biopharmaceutical company focusing on the development of small molecule drugs for the treatment of edema and angiogenesis related diseases, today announced that the Company has received notification from the FDA granting Fast Track Designation for TargeGen's TG100-115 for the treatment of acute ST-elevation myocardial infarction (STEMI). TG100-115 is currently being tested in a multi-center, double blinded, placebo controlled, Phase I/II clinical trial involving approximately 70 patients. The Company expects completion of this trial by the end of 2006.

"Fast Track Designation" recognizes the need to expedite the development and review of novel drugs that potentially treat life threatening conditions. Fast Track Drug Sponsors may receive various forms of assistance from the FDA which potentially facilitate more efficient new drug development and shorten approval times.

TargeGen is currently working on the development of four internally discovered drug candidates. These include TG100-115, a compound which received the UCSD Connect Most Innovative Product of the Year Award in 2004. Heart attacks are the leading disease related cause of death in the developed world. TargeGen is also working on the development of novel drugs to treat debilitating eye diseases and myeloproliferative diseases.

About TargeGen, Inc.

TargeGen, Inc. is a privately held vascular biology focused biopharmaceutical company based in San Diego, CA. TargeGen is developing novel small molecule therapeutics to treat diseases that involve edema, angiogenesis and inflammation as key elements of disease pathology by selectively targeting certain kinases associated with the formation and repair of blood vessels, vascular permeability (edema) and inflammation.

TargeGen, which initiated operations in 2002, has raised more than $70M from top tier venture capital sources. Key investors include Forward Ventures, Enterprise Partners, William Blair Capital Partners/Chicago Growth Partners, CDP Capital Technology Ventures/Vantage Point Venture Partners, BB BIOTECH VENTURES, Hambrecht & Quist Capital Management LLC, Pappas Ventures and other investors.

Source: TargeGen

Issuer of this News Release is solely responsible for its content.
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