Healthcare Industry News:  Frank Condella 

Biopharmaceuticals Personnel

 News Release - September 22, 2006

SkyePharma to Reorganise Certain Management Functions

LONDON, Sept. 22 (HSMN NewsFeed) -- SkyePharma PLC (LSE: SKP ; Nasdaq: SKYE ) announces today that as part of the Company's ongoing initiatives to increase operational efficiency the Board has decided to out- source investor relations and to restructure the legal and company secretarial functions. By mutual agreement Peter Laing, Director of Corporate Communications, and Douglas Parkhill, Company Secretary, will be leaving the Company.

Frank Condella, SkyePharma's Chief Executive, said: "We thank Peter and Douglas for their meritorious service in their respective roles and wish them every success in the future."

For further information please contact:

SkyePharma PLC +44 207 491 1777
Frank Condella, Chief Executive Officer

Buchanan Communications +44 207 466 5000
Tim Anderson / Mark Court / Rebecca Skye Dietrich

The Trout Group
Seth Lewis +1 617 583 1308

About SkyePharma

SkyePharma PLC develops pharmaceutical products benefiting from world- leading drug delivery technologies that provide easier-to-use and more effective drug formulations. There are now eleven approved products incorporating SkyePharma's technologies in the areas of oral, injectable, inhaled and topical delivery, supported by advanced solubilisation capabilities. For more information, visit www.skyepharma.com.

Certain statements in this news release are forward-looking statements and are made in reliance on the safe harbour provisions of the U.S. Private Securities Litigation Act of 1995. Although SkyePharma believes that the expectations reflected in these forward-looking statements are reasonable, it can give no assurance that these expectations will materialize. Because the expectations are subject to risks and uncertainties, actual results may vary significantly from those expressed or implied by the forward-looking statements based upon a number of factors, which are described in SkyePharma's 20-F and other documents on file with the SEC. Factors that could cause differences between actual results and those implied by the forward-looking statements contained in this news release include, without limitation, risks related to the development of new products, risks related to obtaining and maintaining regulatory approval for existing, new or expanded indications of existing and new products, risks related to SkyePharma's ability to manufacture products on a large scale or at all, risks related to SkyePharma's and its marketing partners' ability to market products on a large scale to maintain or expand market share in the face of changes in customer requirements, competition and technological change, risks related to regulatory compliance, the risk of product liability claims, risks related to the ownership and use of intellectual property, and risks related to SkyePharma's ability to manage growth. SkyePharma undertakes no obligation to revise or update any such forward-looking statement to reflect events or circumstances after the date of this release.


Source: SkyePharma

Issuer of this News Release is solely responsible for its content.
Please address inquiries directly to the issuing company.



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