Healthcare Industry News:  Sequenom 

Biopharmaceuticals Personnel Mergers & Acquisitions

 News Release - October 25, 2006

Forbes Medi-Tech to Acquire San Diego Based TheraPei Pharmaceuticals and Appoint Dr. John Nestor as Chief Scientific Officer

Acquisition will diversify the Company's Drug development pipeline; R&D to be consolidated under the direction of new CSO

VANCOUVER, BRITISH COLUMBIA--(Healthcare Sales & Marketing Network)--Oct 25, 2006 -- Forbes Medi-Tech Inc. (TSX:FMI.TO )(NASDAQ:FMTI ) today announced that it has signed an agreement to acquire 100% of TheraPei Pharmaceuticals, Inc.(TheraPei) of San Diego, California. TheraPei is a privately held company formed with technology 'spun-out' of Sequenom, Inc. (NASDAQ:SQNM ) focused on developing novel pharmaceuticals directed at the underlying causes of type II diabetes and related metabolic diseases. Forbes will further develop TheraPei technologies along with Forbes' existing technologies with R&D based in San Diego and Forbes' clinical development team in Vancouver. TheraPei's founder, Dr. John Nestor, will be appointed as the Chief Scientific Officer of Forbes on closing.

Consideration for the acquisition will be made on a staged basis commensurate with development of the newly acquired technologies. The acquisition consideration will consist of a small upfront payment, the issuance of common shares not to exceed 150,000 on closing plus future consideration consisting of milestone payments, licensing revenue and/or royalties. Potential milestone payments may reach up to US$50 million based upon the successful completion of key clinical development steps. Dr. Nestor is the majority shareholder of TheraPei and as such, will receive the majority of the acquisition consideration. Sequenom holds a minority shareholder interest in TheraPei.

All consideration shall be paid as to a minimum of 80% in common shares of Forbes, subject to regulatory and shareholder approval as required, and the balance, up to 20%, in cash. If regulatory or shareholder approval is not forthcoming, Forbes shall pay cash in lieu of the issuance of shares. Forbes may also elect to pay cash in lieu of the issuance of shares in certain circumstances.

"With Forbes' lead compound, FM-VP4, nearing completion of Phase II in the US, the Company has the development team and capabilities required to fully realize the significant potential of TheraPei's novel drug candidates," noted Charles Butt, President and CEO, Forbes Medi-Tech Inc. "Dr. Nestor's extensive track record of successful drug discovery and development will help us optimize Forbes' existing FM-VPx library."

Acquired Intellectual Property

The TheraPei Intellectual Property will add diversity to Forbes' FM-VPx drug development platform to include four new technologies: a series of novel peptides designed for once daily administration aimed at stimulating insulin secretion; compounds from this series are also being developed for potential anti-inflammatory effects; an earlier stage discovery program that may have important applications in both diabetes and obesity through inhibition of ACC2; and another discovery program related to SPT inhibition targeting anti-inflammation.

The lead preclinical product is a peptide that is targeted to be a long acting VPAC2 selective agonist designed for once daily administration to stimulate insulin secretion. These analogues are particularly promising based on pre-clinical study results to date demonstrating a beneficial effect through lowering glucose in blood, which could benefit a large diabetic patient population.

Diabetes represents a significant market opportunity with annual sales expected to reach about $25 billion by 2011 according to DataMonitor. It is believed that VPAC2 selective agonists will target insulin secretion via a different pathway than BYETTA®(i) (launched in 2005, with forecasted sales of $1 billion in 2007) leading to a differentiated product profile in this increasingly important class. The same agonists are also generally believed to play a role as inflammatory mediators in a number of other physiological conditions, creating a much broader utility for this technology.

Appointment of Dr. John Nestor as Chief Scientific Officer of Forbes Medi-Tech Inc.

Dr. Nestor's responsibilities will encompass both the advancement of the technology that he developed under TheraPei as well as the optimization of Forbes' existing FM-VPx pipeline. Before founding TheraPei, Nestor served as Executive Vice President, Drug Discovery at Sequenom; Vice President & Director at the Institute of Bio-organic Chemistry, Syntex; and Distinguished Scientist at Roche Bioscience. Dr. Nestor is an inventor of 10 compounds selected for clinical development and the lead inventor on 3 currently marketed pharmaceuticals. He is co-inventor on more than 45 U.S. Patents, author of more than 60 scientific articles, Editor of 2 books, and Associate Editor, Letters in Drug Design and Discovery. Recently, he was an invited Chapter Author for Comprehensive Medicinal Chemistry II (Elsevier, 2006), contributing "Peptide and Protein Drugs: Issues and Solutions". Dr. Nestor has more than 25 years of leadership experience in drug discovery/development programs in major pharma and biotech.

"I look forward to working with the Forbes development team, which I am confident will maximize the value of TheraPei's technology while I continue to focus on the discovery of novel therapies in the fight against metabolic disorders by addressing their underlying causes," stated Dr. Nestor.

Closing is subject to standard closing conditions and is expected to occur within the next week.

About TheraPei Pharmaceuticals

Founded in 2004, TheraPei's management and core technology were "spun out" of the Drug Discovery Unit of Sequenom. TheraPei's Research is focused on the discovery and development of novel pharmaceuticals directed at the underlying causes of type 2 diabetes and the metabolic syndrome.

About Forbes Medi-Tech Inc.

Forbes Medi-Tech Inc. is a life sciences company dedicated to the research, development and commercialization of innovative products for the prevention and treatment of cardiovascular disease (CVD). Our vision is to develop and market products along a treatment continuum that CVD savvy consumers, healthcare professionals and specialized CVD research and healthcare institutions will identify, recommend and seek. Our business strategy is to develop and commercialize proprietary compounds to address the unmet needs of patients within the cardiovascular disease market.

(i)BYETTA is a registered trademark of Amylin Pharmaceuticals, Inc.

Forbes Medi-Tech ("Forbes" or the "Company") has relied solely on Sequenom Inc. for the information about Sequenom provided in this News Release and the Company disclaims any liability with respect to such information. This News Release contains forward-looking statements regarding, among other things, the planned acquisition of Therapei and appointment of John Nestor as CSO, potential milestone payments, Therapei's technology, including without limitation its VPAC2 selective agonists, Forbes' existing FM-VPx library, diabetes products and markets, and Forbes' strategy and vision, which statements can be identified by the use of forward-looking terminology such as "will", "further", "potential", "targeted", "believed", "opportunity", "expected", forward", "strategy", "vision", "to develop", "could", or comparable terminology referring to future events or results. The Company's actual results could differ materially from those anticipated in these forward-looking statements as a result of numerous factors, including uncertainty whether the proposed acquisition of Therapei will close, and the proposed appointment of John Nestor as CSO will occur, within the next week or at all; uncertainty regarding the amount, timing and nature of future milestone payments; the need for additional research, the outcome of which is uncertain; the need for clinical trials, the occurrence and success of which is not assured; the need for regulatory approvals, which are not assured and which may be denied or withdrawn; uncertainty whether the Company will realize is strategies and vision; intellectual property risks; manufacturing risks and the need to manufacture to regulatory standards; product liability and insurance risks; marketing risks; the risk of unknown side effects; the effect of competition; changes in business strategy or development plans; and the Company's need for future funding; as well as a description of other risks and uncertainties affecting the Company and its business, as contained in news releases and filings with Securities Regulatory Authorities in Canada and the U.S., any of which could cause actual results to vary materially from current results or the Company's anticipated future results. Forward-looking statements are based on the beliefs, opinions and expectations of the Company's management at the time they are made, and the Company does not assume any obligation to update any statement should those beliefs, opinions or expectations, or other circumstances change.

NASDAQ and the Toronto Stock Exchange have not reviewed and do not accept responsibility for the adequacy or accuracy of the content of this News Release.

Source: Forbes Medi-Tech

Issuer of this News Release is solely responsible for its content.
Please address inquiries directly to the issuing company.

FindReps - Find Great Medical Independent Sales Reps without recruiter fees.
FindReps - available on the Apple App Store for iPhone and iPad.