Devices Interventional Cardiology Regulatory

 News Release - May 12, 2008

Medinol Receives CE Mark for Presillion(TM) Cobalt Chromium Coronary Stent on Rx System, an Advanced Evolution of the NIR(R) Family of Stents

Provides the Optimal Combination of Scaffolding, Deliverability and Conformability

TEL AVIV, Israel, May 12 (HSMN NewsFeed) -- Medinol is proud to announce that it has received CE Mark for its Presillion(TM) CoCr Coronary Stent, enabling physicians to treat coronary artery lesions with a technologically innovative flexible closed cell design stent.

Presillion(TM) preserves the superb scaffolding the unprecedented balance of flexibility and conformability identified with the NIRflex flexible closed cell design. The unique geometry of the Presillion(TM) complies with the long term needs of patients for both safety and efficacy in addition to ease of delivery for the physicians. The alternating rings provide simultaneously optimal flexibility and enhanced scaffolding. Dr. Kobi Richter, chairman of the board and chief technology officer of Medinol says, "Cobalt Chromium enables us to reduce the strut thickness and overall cell size by up to 25% compared to stainless steel while retaining superior scaffolding through the unique flexible closed cell design; this material also maintains a much higher fatigue resistance and radiopacity than the common stainless steel stents."

"Medinol is proud to introduce a new family of stent systems to the market, the first of which is the Presillion(TM). By utilizing its expertise and IP Medinol is proving itself once again as a leading developer, designer and manufacturer of stents and stent systems," says Dr. Judith Richter, chief executive officer for Medinol.

Medinol partnered with Cordis, a Johnson and Johnson company, last year, and will be distributing the Presillion globally. "We are happy that we are able to enrich Cordis's Cath Lab Cubed offer to market," says Dr. Richter.

Recent research recognized the value of Bare Metal Stents and the growing versatility of treatments of complex coronary artery disease. The introduction of the Presillion enhances the physicians' ability to choose the most suitable stent for each patient and the long term benefits provided for each individual vessel and lesion.

The Presillion comes in diameters ranging from 2.5-4.0 mm. and in lengths ranging from 8-32 mm. The Presillion stent system and can be used to treat various lesion types: de novo, restenotic lesions, total occlusions, bifurcations, and acute myocardial infarction.

Medinol continues setting new standards in the stenting industry through design innovation and advance technology manufacturing methods. Medinol is constantly enhancing its technology and producing stenting solutions for: coronary and vascular systems, bifurcation stenting and Biliary Stenting. Medinol is currently developing advanced technology stents and additional therapeutic solutions for the treatment of vascular disease that will be introduced to the market in the near future.

Source: Medinol

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