Healthcare Industry News:  linear accelerator 

Devices Oncology

 News Release - October 22, 2008

Next Generation CyberKnife System Cuts Prostate Cancer Treatment Times in Half at CyberKnife Centers of San Diego

Technological Advancements Enable Highly-Complex Treatments to be Delivered in Routine Clinical Practice

SUNNYVALE, Calif., Oct. 22 (Healthcare Sales & Marketing Network) -- Accuray Incorporated (Nasdaq: ARAY ), a global leader in the field of radiosurgery, announced today that CyberKnife Centers of San Diego has shortened prostate cancer treatment times, while further improving the quality of treatment plans, by upgrading one of its CyberKnife® Robotic Radiosurgery Systems with the next-generation technology. CyberKnife treatment delivery for prostate cancer, which used to take nearly two hours, now can be completed in an hour or less, and requires only five or fewer outpatient visits.

The next generation CyberKnife technology includes a sequential optimization planning tool for the efficient development of highly-complex treatment plans, a higher output linear accelerator to more rapidly deliver dose to the target, and the Iris(TM) Variable Aperture Collimator, which enables delivery of very conformal, multi-collimator treatments. The upgraded System also utilizes optimized path transversal technology to support more efficient movement of the robotic linear accelerator, speeding treatment time even more.

"The improvements to the CyberKnife System have exceeded my highest expectations," said Donald B. Fuller, M.D., a radiation oncologist with the CyberKnife Centers of San Diego and Radiation Medical Group. "The combination of these sophisticated tools enables us to develop amazingly conformal plans, and deliver them far more rapidly than before. Together these enhancements create the most advanced CyberKnife platform in existence - 'the next knife' if you will."

"The flexibility of the CyberKnife System has enabled us to provide a non- invasive prostate cancer therapy that closely resembles the radiation dose pattern delivered by high dose rate - or HDR - brachytherapy without the pain and discomfort," said Dr. Fuller.

Historically, HDR brachytherapy has shown considerable success in controlling many prostate cancers, optimally matching the highest radiation dose with the greatest cancer cell burden, yet the procedure requires multiple catheters to be inserted into the prostate, and remain there for one to three days. Accordingly, HDR brachytherapy has left both clinicians and patients looking for less invasive, more cost-effective alternatives.

Currently, Dr. Fuller is leading a study to further investigate both outcomes and quality of life effects of CyberKnife radiosurgery in treating low and intermediate risk prostate cancer using HDR-like - dose distributions. Earlier this year he published a study in the International Journal of Radiation Oncology*Biology*Physics - also known as the Red Journal - demonstrating the CyberKnife System's ability to non-invasively deliver complex HDR-like radiation dose sculpting to the prostate. Initial results of the study demonstrated a rapid reduction in prostate specific antigen (PSA) levels as well as minimal short-term side effects.

"In addition to addressing clinicians' needs, we're always taking into consideration the patients' experience when we develop enhancements to the CyberKnife System," said Eric P. Lindquist, senior vice president and chief marketing officer of Accuray. "By enabling shorter treatment times with a non- invasive delivery, we are helping prostate cancer patients avoid painful and lengthy procedures that can significantly impact their quality of life."

About the CyberKnife® Robotic Radiosurgery System

The CyberKnife Robotic Radiosurgery System is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non- invasively. Using continual image guidance technology and computer controlled robotic mobility, the CyberKnife System automatically tracks, detects and corrects for tumor and patient movement in real-time throughout the treatment. This enables the CyberKnife System to deliver high-dose radiation with pinpoint precision, which minimizes damage to surrounding healthy tissue and eliminates the need for invasive head or body stabilization frames.

About Accuray

Accuray Incorporated (Nasdaq: ARAY ), based in Sunnyvale, Calif., is a global leader in the field of radiosurgery dedicated to providing an improved quality of life and a non-surgical treatment option for those diagnosed with cancer. Accuray develops and markets the CyberKnife Robotic Radiosurgery System, which extends the benefits of radiosurgery to include extracranial tumors, including those in the spine, lung, prostate, liver and pancreas. To date, the CyberKnife System has been used to treat more than 50,000 patients worldwide and currently more than 140 systems have been installed in leading hospitals in the Americas, Europe and Asia. For more information, please visit

Safe Harbor Statement

The foregoing may contain certain forward-looking statements that involve risks and uncertainties, including uncertainties associated with the medical device industry. Except for the historical information contained herein, the matters set forth in this press release, including statements relating to clinical studies, regulatory review and approval, and commercialization of products are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements speak only as of the date the statements are made and are based on information available at the time those statements are made and/or management's good faith belief as of that time with respect to future events. You should not put undue reliance on any forward-looking statements. Important factors that could cause actual performance and results to differ materially from the forward-looking statements we make include: market acceptance of products; competing products, the combination of our products with complementary technology; and other risks detailed from time to time under the heading "Risk Factors" in our report on Form 10-K for the year ended June 30, 2008 as updated from time to time by our quarterly reports on Form 10-Q and our other filings with the Securities and Exchange Commission. The Company's actual results of operations may differ significantly from those contemplated by such forward-looking statements as a result of these and other factors. We assume no obligation to update forward-looking statements to reflect actual performance or results, changes in assumptions or changes in other factors affecting forward-looking information, except to the extent required by applicable securities laws.

Source: Accuray

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