




Healthcare Industry News: Magnetic Resonance Imaging
News Release - April 1, 2009
NIMS Exer-Rest(R) Technology Linked to Reduced Brain Damage in Strokes
MIAMI--(HSMN NewsFeed)--Non-Invasive Monitoring Systems, Inc. [NIMS] (OTCBB:NIMU ) announced today that the results of a laboratory investigation published in the April issue of the journal Neuroscience links the technology behind NIMS’ patented Exer-Rest(R) acceleration therapeutic platform to a reduction in brain damage for the major cause of stroke. In their report, “Whole-body periodic acceleration (pGz) reduces brain damage in a focal ischemia model,” Drs. Martinez-Murillo, Serrano, Fernandez and Martinez of CSIC and CIBIR, Madrid & Logroño, Spain concluded that whole body periodic acceleration (WBPA, pGz), the technology behind the Exer-Rest(R), has potential to positively impact on the management of stroke, the third leading cause of death and the major cause of significant disability in adults living in the USA and Europe. They selected this treatment because it increases release of beneficial substances, such as nitric oxide, prostacyclin, prostaglandin E2, and adrenomedullin, from the inner lining of blood vessels into the circulation. These substances protect the brain from damage due to ischemia, i.e., cessation of blood flow to tissue. In their study, the investigators simulated occlusion of a brain blood vessel with clot, the cause of 85% of human strokes. In one group of rats, WBPA was administered for three hours immediately following the simulated stroke, while no treatment was provided to a control group. Magnetic Resonance Imaging (MRI) conducted 7 days after the simulated stroke revealed 82% less dead brain tissue in the WBPA-treated rats than in the untreated control group. In addition, biochemical markers of brain damage were significantly lower in the WBPA-treated animals.Steven Mrha, Chief Operating Officer of NIMS stated that WBPA is achieved in humans with the Exer-Rest(R) acceleration therapeutic platform. The Exer-Rest(R) in an FDA approved Class I (exempt) medical device with the following intended uses: “as an aid to temporarily increase local circulation, to provide temporary relief of minor aches and pains, and local muscle relaxation.” The Exer-Rest(R) is a motorized platform that has the appearance of a single or twin bed with a memory foam mattress. A person lying on the mattress is moved repetitively head to foot approximately 140 times per minute during a 30 to 45 minute session. These treatments are usually administered daily five to seven days a week for symptomatic relief. The Exer-Rest(R) WBPA technology is covered by five US patents.
NIMS, an ISO 13485 certified company, is also licensed to sell Exer-Rest(R) in Canada, United Kingdom, the European Common Market and other major world markets. Exer-Rest(R) is regulated outside of the United States as a Class IIa medical device with CE certification.
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Source: Non-Invasive Monitoring Systems
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