Healthcare Industry News:  mTOR pathway 

Biopharmaceuticals Venture Capital

 News Release - July 8, 2009

Intellikine Completes $51 Million Financing

LA JOLLA, Calif., July 8 -- (Healthcare Sales & Marketing Network) -- Intellikine, Inc., a leader in the development of innovative, small molecule drugs for the treatment of cancer, inflammation and autoimmune diseases, announced today that it has raised $51 million in preferred stock financing. Novartis Bioventures Ltd. led the financing in which additional new investors U.S. Venture Partners, Biogen Idec and FinTech Global Capital participated. Markus Goebel, M.D., Ph.D., Managing Director of the Novartis Venture Funds, will join the company's board of directors.

The investment includes a $28.5 million first closing. In addition, the company can access up to another $22.5 million, subject to the performance of certain milestones, which, if triggered, will bring the total amount raised in this round to $51 million. This latest financing comes less than two years after the company was formed with an initial investment of $12.5 million from founding investors Abingworth, CMEA Capital and Sofinnova Ventures, all of whom participated in this latest financing.

Intellikine is developing a portfolio of isoform-selective inhibitors of the phosphatidyinositol-3-kinase (PI3K) pathway for the treatment of cancer, inflammation and autoimmune diseases. The company has discovered multiple classes of proprietary compounds that are potent, selective and druglike inhibitors of PI3K isoforms. The company's most advanced compound, INK128, a selective TORC1/2 inhibitor, has demonstrated efficacy in multiple models of cancer and is expected to enter Phase I clinical studies within twelve months.

"We are delighted to have generated such excitement among both new and existing investors," said Troy Wilson, Ph.D., J.D., President and Chief Executive Officer of Intellikine. "This financing gives us the resources necessary to advance our pipeline of PI3K/mTOR inhibitors into clinical development as well as significant flexibility to build strategic partnerships to deliver the best medicines for patients and the greatest value for our investors."

"Intellikine has rapidly assembled one of the best pipelines against a very important class of drug targets," commented Markus Goebel, Managing Director, Novartis Venture Funds. "I am very much looking forward to working with the management team and board to build the company and, in particular, to establish clinical proof of concept for the company's lead programs."

About Intellikine

Intellikine is a leader in the discovery and development of novel, small molecule therapies targeting the PI3K/mTOR pathway for the treatment of cancer, inflammation and autoimmune diseases. Intellikine has discovered multiple classes of proprietary compounds that selectively target isoforms of the PI3K pathway. The company's most advanced compound, INK128, a potent and selective TORC1/2 inhibitor with exceptional drug-like properties is scheduled to enter Phase I clinical evaluation within 12 months. Intellikine is developing PI3K-delta/gamma dual-selective inhibitors for the treatment of cancer, inflammatory and respiratory diseases and PI3K-alpha/beta selective inhibitors for the treatment of solid tumor malignancies as well as other isoform-selective inhibitors of the PI3K/mTOR pathway. Intellikine is a private company based in La Jolla, California. For more information, please visit the company's website at www.intellikine.com.


Source: Intellikine

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