Healthcare Industry News:  Isis Pharmaceuticals 

Biopharmaceuticals Personnel

 News Release - February 15, 2011

Aegerion Pharmaceuticals Appoints Diane L. Tribble, Ph.D., M.M.Sc., as Chief Scientific Officer

Lipids Expert Adds Extensive Experience in Cholesterol-Lowering Drug Development

CAMBRIDGE, Mass., Feb. 15, 2011 -- (Healthcare Sales & Marketing Network) -- Aegerion Pharmaceuticals, Inc. (Nasdaq:AEGR ), an emerging biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat severe lipid disorders, announced the appointment of Diane L. Tribble, Ph.D., M.M.Sc. to its executive team as Chief Scientific Officer.

Dr. Tribble was most recently Vice President of Clinical Development at Isis Pharmaceuticals, where she led the development of the cholesterol-reducing antisense therapeutic, mipomersen, which is currently in late-stage clinical development.

Prior to her role at Isis, Dr. Tribble was Director of Clinical Research at the Merck Research Laboratories, of Merck & Co. where she worked on the development of several cholesterol-reducing drug candidates, including the CETP inhibitor, anacetrapib, intended to treat hypercholesterolemia, and Vytorin(R). At Merck, Dr. Tribble was also a member of the Cholesterol Task Force of the Merck/Schering-Plough joint venture.

Aegerion's Chief Executive Officer Marc Beer commented, "Diane's demonstrated success developing drugs in the lipid space is impressive, and it makes her a valuable asset to Aegerion. We believe her decision to join our team validates the promise of our drug candidate, lomitapide. We are very pleased to have Diane on board as we finalize our clinical trial and prepare for NDA filing. This addition to our management team gives me added confidence in our ability to advance our clinical program as we seek to offer this critically important product to the patients in need."

Dr. Tribble added, "I'm excited to join the management team at Aegerion, and I look forward to utilizing my development experience with other lipid-lowering drugs to bring lomitapide through the final stages of clinical development, submission and approval."

About Aegerion Pharmaceuticals, Inc.

Aegerion Pharmaceuticals, Inc. (Nasdaq:AEGR ) is an emerging biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat severe lipid disorders. The Company's lead product, lomitapide, is in Phase III clinical development. Lomitapide is initially being developed to treat patients with a rare genetic lipid disorder called homozygous familial hypercholesterolemia, or HoFH. The Company also plans to initiate a clinical program for lomitapide to treat patients with a severe genetic form of hypertriglyceridemia called familial chylomicronemia.

Forward-Looking Statements

This press release contains forward-looking statements which are made pursuant to the safe harbor provisions of Private Securities Litigation Reform Act of 1995, including statements regarding expected regulatory filings for and commercialization of the Company's lead product candidate, lomitapide. The forward-looking statements in this release do not constitute guarantees of future performance. These statements are neither promises nor guarantees, and are subject to a variety of risks and uncertainties, many of which are beyond the Company's control, which could cause actual results to differ materially from those contemplated in these forward-looking statements. In particular, the risks and uncertainties include, among other things: our history of operating losses; our potential need for additional capital to fund operations and develop our product candidates; uncertainties associated with the clinical development and associated regulatory filings of our product candidates, including the risk that our regulatory filings may not be accepted by the applicable regulatory authorities, the risk that our product candidates may not be approved for any indication, or if approved, the risk that the finally approved definition of the targeted patient populations for our product candidates may be narrower than we expect; risks associated with undesirable side effects experienced by some patients in clinical trials for our product candidates; risks associated with our lack of sales and marketing experience; the highly competitive industry in which we operate; risks associated with our intellectual property rights and the extent to which such intellectual property rights protect our product candidates; the risk that third parties may allege that we infringe their intellectual property rights or that we have failed to comply with the provisions of our in-license agreements; risks associated with our reliance on third parties, in particular clinical research organizations and contract manufacturers; risks associated with our ability to recruit, hire and retain qualified personnel; and risks associated with volatility in our stock price as a newly public company. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to update or revise the information contained in this press release, whether as a result of new information, future events or circumstances or otherwise. For additional disclosure regarding these and other risks faced by the Company, see the disclosure contained in our public filings with the Securities and Exchange Commission, including the Company's most recent Quarterly Report on Form 10-Q under the heading "Risk Factors" and available on its investor relations website at and on the SEC's website at

Source: Aegerion Pharmaceuticals

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