Healthcare Industry News:  Acute Coronary Syndrome 

Devices Interventional Cardiology

 News Release - February 14, 2013

Miracor Granted Five Additional U.S. Patents and One Additional European Patent for Its PICSO(R) System to Treat Severe Heart Attack Patients

IP protection includes PICSO® method and algorithms that ensure stable and repeatable PICSO® treatment designed to enhance myocardial perfusion following primary PCI in STEMI patients

VIENNA--(Healthcare Sales & Marketing Network)--Miracor Medical Systems GmbH announced today that 2012 was a record patent year with five new U.S. patents granted and an additional European patent protecting intellectual property related to its novel PICSO® (Pressure-controlled Intermittent Coronary Sinus Occlusion) system and algorithms that ensure a stable and repeatable PICSO® treatment designed to improve myocardial perfusion following primary PCI (Percutaneous Coronary Intervention, or angioplasty). (Click here for video animation of PICSO®.)

The Miracor PICSO® Impulse System, which is CE-marked, is designed to treat acute heart attack STEMI patients following a coronary angioplasty. ‘STEMI’ is an acronym meaning ST-segment Elevation Myocardial Infarction. Heart attacks are divided into three types, according to their severity. A STEMI heart attack is the most severe type. In a STEMI heart attack, the coronary artery is completely blocked off by the blood clot, and as a result virtually all the heart muscle being supplied by the affected artery starts to die.

“Despite a successful coronary angioplasty, impaired myocardial reperfusion still manifests in about one in three STEMI patients, and this unsatisfactory incidence is strongly correlated with unfavorable outcomes for patients,” said Jon H. Hoem, Miracor CEO. “PICSO is designed to solve this life-threatening problem by dramatically amplifying the redistribution of blood into the blood-starved myocardium of severe heart attack patients post-PCI,” added Hoem. “We have been extremely diligent about protecting our IP throughout the U.S., Europe and Japan, and will continue to do so as we further enhance the features and benefits of PICSO.”

About PISCO®

Timely myocardial reperfusion using primary Percutaneous Coronary Intervention (PCI) remains the most effective treatment strategy for limiting infarct size, reducing left ventricular remodeling, and improving clinical outcomes following ST-segment elevation myocardial infarction (STEMI). Despite optimum primary PCI, the mortality and morbidity following a STEMI event remains sizable. Clearly, primary PCI alone is not enough to eliminate the risk for future cardiovascular events. Paradoxically, the process of restoring coronary blood flow can in itself exacerbate the myocardial injury. Miracor’s Pressure-controlled Intermittent Coronary Sinus Occlusion (PICSO®) Impulse System offers a new and innovative approach to reduce myocardial injury and to revitalize ischemic myocardium. Initial clinical results show positive effects on MACE, restenosis rates, and long-term event-free survival. The PICSO® system consists of the Miracor PICSO® Impulse Console and the disposable, single-use Miracor PICSO® Impulse Catheter.

About Miracor Medical Systems GmbH

Based in Vienna, Austria, privately held Miracor is commercializing a unique and potentially disruptive technology, PICSO®, for Acute Coronary Syndrome (ACS), heart failure, and cardiac surgery patients. The Company’s objective is to establish PICSO® as the standard of care for heart attack patients, thereby improving their quality of life. The initial market opportunity for PICSO® is 30% of all ACS patients treated per year, which translates into more than 350,000 patients in the U.S. and Europe.

The Miracor PICSO® Impulse System is CE-marked and can be used during coronary revascularization procedures following myocardial infarction and other types of Acute Coronary Syndromes to intermittently increase the pressure in the coronary venous system. The technology is for investigational use only in the United States at this time.


Source: Miracor Medical Systems

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