Healthcare Industry News:  Partial Knee 

Devices Orthopaedic

 News Release - May 23, 2013

New U.S. Study Indicates that Biomet’s Oxford Partial Knee Patients were More Likely to be Satisfied than Total Knee Patients in Ability to Perform Activities of Daily Living

WARSAW, Ind.--(Healthcare Sales & Marketing Network)--Biomet, Inc., a global leader in the manufacture of orthopaedic and biotechnology products, announces the presentation of research that included an evaluation of patient satisfaction with its Oxford Partial Knee. The study reports that patients in the study who received the Oxford Partial Knee were 1.8 times more likely than total knee replacement recipients to report that their knee felt normal, and 2.7 times more likely to be satisfied with their ability to perform activities of daily living, at a minimum of one year post-operation.*

Jeff Binder, President and CEO of Biomet, Inc., stated, “This landmark research definitively shows that patient experiences with different knee replacement products can widely vary. Biomet is committed to the further development of joint replacement technologies that improve patient satisfaction by helping people with advanced arthritis return to their daily activities with significantly greater mobility and less pain.”

Craig Della Valle, MD, Associate Professor of Orthopaedic Surgery at Rush University Medical Center, and one of the investigators in this study, stated, “The data are impressive as were the scientific methods to collect them. Given the importance of patient satisfaction to both those undergoing knee replacement as well as their surgeons, it is a further compelling reason to consider Partial Knee replacement in patients who are candidates for the procedure.”

The multi-center study was led by researchers at Washington University in St. Louis, Missouri. Patients included in the study were treated with either total knee replacement, fixed-bearing unicompartmental knee replacement, or the Oxford Partial Knee. Centers contributing data on both total knee and Partial Knee replacement were Washington University, St. Louis, Missouri; Rush University Medical Center, Chicago, Illinois; and Mt. Carmel Hospital, New Albany, Ohio. Data for the study were gathered through comprehensive interviews, conducted by the University of Wisconsin, of 1,263 consecutively identified arthroplasty patients who met the inclusion/exclusion criteria.

The study adds to the published clinical research on the Oxford Partial Knee, the most widely-used and clinically proven1-4 Partial Knee available in the world. Clinical data indicate 15-year survivorship of 94% following surgery1,2,4. Additionally, studies have indicated that Oxford Partial Knee patients have demonstrated more normal motion,5,6 less pain,7,8 and faster recovery9 as compared to total knee replacement patients.

Study co-author Michael E. Berend, MD presented the results on May 20, during the Current Concepts in Joint Replacement meeting in Las Vegas, Nevada. Dr. Berend is an orthopaedic surgeon at the Center for Hip and Knee Surgery, Mooresville, Indiana, and also conducts research in conjunction with the Joint Replacement Surgeons of Indiana Research Foundation, and the Orthopedic Biomechanical Engineering Laboratory, Rose Hulman Institute of Technology.

Indications and Contraindications (United States only)

The Oxford Partial Knee is intended for use in individuals with osteoarthritis or avascular necrosis limited to the medial compartment of the knee and is intended to be implanted with bone cement. The Oxford Knee is not indicated for use in the lateral compartment and patients with ligament deficiency. For full prescribing information, including indications, contraindications, warnings, and patient selection considerations, please see the package insert and the “Patient Risk Information” section of www.biomet.com.

About Biomet

Biomet, Inc. (www.biomet.com) and its subsidiaries design, manufacture and market products used primarily by musculoskeletal medical specialists in both surgical and non-surgical therapy. Biomet’s product portfolio encompasses large joint reconstructive products, including orthopedic joint replacement devices, and bone cements and accessories; sports medicine, extremities and trauma products, including internal and external orthopedic fixation devices; spine and bone healing products, including spine hardware, spinal stimulation devices, and orthobiologics, as well as electrical bone growth stimulators; dental reconstructive products; and other products, including microfixation products and autologous therapies. Headquartered in Warsaw, Indiana, Biomet and its subsidiaries currently distribute products in approximately 90 countries.

*Adjusted odds ratio controlled for gender, age, minority, income, and center.

1. Svard, U. and Price, A. Oxford Medial Unicompartmental Knee Arthroplasty. A Survival Analysis of an Independent Series. Journal of Bone and Joint Surgery. 83:191–194. 2001

2. Price AJ, Svard U.: A second decade lifetable survival analysis of the Oxford unicompartmental knee arthroplasty. Clin Orthop Relat Res. 2011 Jan;469(1): 174-9

3. Emerson RH Jr, Higgins LL. Unicompartmental knee arthroplasty with the Oxford prosthesis in patients with medial compartment arthritis. Journal of Bone and Joint Surgery. 2008 Jan;90(1):118-22

4. Price, A. et al. Long-term Clinical Results of the Medial Oxford Unicompartmental Knee Arthroplasty. Clinical Orthopedics and Related Research. 435:171–180. 2005

5. Price, AJ, et al. Simultaneous in vitro measurement of patellofemoral kinematics and forces following Oxford medial unicompartmental knee replacement. JBJS (Br). 2006; 88-B; 12: 1591-1595

6. Data on File. Cobb, J, et al. Functional Assessment of knee arthroplasty using an instrumented treadmill. Imperial College of London Presentation March 8, 2012.

7. Hopper, PG., Leach, WJ. Participation in sporting activities following total knee replacement: total versus unicompartmental. Knee Surgery Sports Traumatology Arthroscopy.2008.16:973-979

8. Hall et al. Unicompartmental Knee Arthroplasty (Alias Uni-Knee)-An Overview with Nursing Implications. Orthopedic Nursing. 2004; 23(3):163-171

9. Lombardi, A. et al. Is Recovery Faster for Mobile-bearing Unicompartmental than Total Knee Arthroplasty? Clinical Orthopedics and Related Research. 467:1450-57.2009 of Daily Living


Source: Biomet, Inc

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