Healthcare Industry News:  Alliqua 

Devices Wound Care

 News Release - July 18, 2013

Alliqua's SilverSeal Dressing Shown to Improve Surgical Wound Outcomes in Clinical Study

Study Results to be Presented at the Annual Meeting of the American Orthopaedic Foot & Ankle Society

LANGHORNE, Pennsylvania, July 18, 2013 -- (Healthcare Sales & Marketing Network) --Alliqua, Inc. (ALQA) ("Alliqua" or the "Company") today announced the results from a post-marketing study to assess surgical wound outcomes in patients who have undergone foot and ankle surgery. In this study, Alliqua's SilverSealĀ® dressing was shown to have a lower incidence of incision complications, including infection, and a greater reduction in scar length compared to standard petroleum-based dressing. Study results are being presented at the annual meeting of the American Orthopaedic Foot & Ankle Society, which is being held in Hollywood, Florida July 17-20.

Stephen A. Brigido, DPM, director of the foot and ankle fellowship at the Coordinated Health Foot and Ankle Center and a primary investigator in the study, stated, "The results from this study are consistent with our preliminary findings reported earlier this year and indicate SilverSeal has potential to not only improve post-surgical incision healing but to reduce healthcare expenditures related to incision complications."

"The reduction in post-surgical incision complications and scarring shown in this study is a meaningful benefit for patients as well as for surgical centers and hospitals. We believe this study demonstrates that SilverSeal can be an effective tool in reducing complications such as infection, and will be useful in driving further adoption," added Philip Forman, Alliqua's EVP of clinical affairs.

In this study, patients who had undergone ankle and foot (including forefoot, midfoot or hindfoot) surgery were randomized to receive either SilverSeal or a standard petroleum-based dressing. Patients were monitored for three months following surgery to assess degree of scarring and the incidence of incision complications such as superficial or deep infections or wound rupture, along the surgical suture. Of the nine incision complications observed, eight occurred in patients using the petroleum-based dressing and only one in those using SilverSeal (p=0.03). Length of post-surgical scarring was also reduced to a greater extent in patients using SilverSeal compared to those with a standard petroleum-based dressing.

These results are summarized in a poster titled "Utilization of Silver Hydrogel Sheet Dressing on Post-Surgical Incisions: A Pilot Study in Foot & Ankle Surgery" that is currently being presented at the American Orthopaedic Foot & Ankle Society annual meeting.

About Alliqua, Inc.

Alliqua, Inc. (ALQA) ("Alliqua") is a biopharmaceutical company focused on the development, manufacturing, and distribution of proprietary transdermal wound care and drug delivery technologies. Alliqua's technology platform produces hydrogels, a 3-dimensional cross-linked network of water soluble polymers capable of numerous chemical configurations.

Alliqua currently markets its new line of 510(k) FDA-approved hydrogel products for wound care under the SilverSealĀ® brand. Alliqua's electron beam production process, located at its 16,000 square foot GMP manufacturing facility in Langhorne PA, allows Alliqua to develop and custom manufacture a wide variety of hydrogels. Alliqua's hydrogels can be customized for various transdermal applications to address market opportunities in the treatment of wounds as well as the delivery of numerous drugs or other agents for pharmaceutical and cosmetic industries. Additionally, Alliqua's drug delivery platform, in combination with certain active pharmaceutical ingredients, can provide pharmaceutical companies with a transdermal technology to enhance patient compliance and potentially extend the patent life of valuable drug franchises.

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Any statements contained in this press release regarding our ongoing research and development and the results attained by us to-date have not been evaluated by the Food and Drug Administration.

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Source: Alliqua

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