Healthcare Industry News: Adaptive Radiation Therapy
News Release - October 28, 2014
RaySearch Laboratories: Raysearch Receives FDA Clearance for RayStation 4.5 Featuring Ultrafast and Robust OptimizationSTOCKHOLM--(Healthcare Sales & Marketing Network)--RaySearch Laboratories AB (publ) (STO:RAYB) has received 510(k) clearance from the FDA for version 4.5 of its treatment planning system RayStation®.
The new version includes a wide range of new features that will help cancer centers improve their treatment planning process and also enable them to take adaptive planning a step further. For example RayStation® 4.5 offers ultrafast and robust optimization for proton and photon treatments, boosted dose calculation, automated breast planning and biomechanical deformable registration using the unique MORFEUS technology.
The ultrafast multi-purpose optimization engine in RayStation®, rayOptimizer, can solve virtually any posed optimization problem within radiation therapy using all degrees of freedom of the treatment unit.
In the 4.5 version, the robust algorithm can take density and patient setup uncertainties into account. This gives the clinicians a structured tool to handle safety margins more efficiently in the planning process which has the potential to further increase the plan quality.
RayStation’s unrivalled speed of optimization and dose computation has also been improved even further in the new version. The dose calculation algorithms have been rewritten entirely and every step in the process has been optimized to improve computation speed. The new version also includes support for optimization and dose computation using the GPU which lets the user benefit from the latest developments in computer technology as well. Together these improvements lead to extremely fast computation speeds. Optimization and clinical dose computation for a standard prostate IMRT case is done in less than ten seconds and even for a more complex 9-beam IMRT head and neck case on a high resolution 2mm dose grid, the optimization and dose computation are executed in approximately 30 seconds.
RayStation® 4.5 includes a major step forward in the field of automated treatment planning. The new rayAutoBreast module provides tools for automated generation of tangential breast IMRT plans using heuristic optimization and includes features such as:
- Automatic detection of radio-opaque markers defining the breast
- Automatic contouring of all the relevant target and risk organs
- Automatic setup of beams, including heuristic optimization of gantry and collimator angles
- Automatic creation of objective functions, optimization and segmentation settings and clinical goals
RaySearch and PMH also collaborate in Adaptive Radiation Therapy and a new feature in RayStation® 4.5 is the MORFEUS technology initially developed by PMH. The unique MORFEUS technology contains a set of algorithms for deformable image registration based on biomechanical modeling of anatomical structures. This makes it possible to track how the radiation dose is delivered to the patient taking into account changes occurring in the patient’s anatomy over the course of treatment. This information can be used to further refine the treatment which has the potential to increase tumor control as well as reduce the risk for side effects. The development and extensive validation of MORFEUS has been documented in several publications in renowned scientific journals.
This know-how is now incorporated in RayStation® and enables cancer centers to take adaptive planning a step further. The advanced biomechanical modeling in MORFEUS incorporates not only the material properties of various anatomical structures, but also how they interact and affect each other. Examples include the sliding interface between the lung and the chest, and structural impact of bronchial tree in the lungs.
“RayStation® 4.5 is a big step forward in our quest to provide a tool that lets the clinicians focus all their skill and experience on evaluating and refining plan quality. The number of menial repetitive tasks is minimized with our tools for automated planning, and in this release we have achieved game-changing computation speed that I think will revolutionize the whole treatment planning work process. As the computation time is measured in seconds rather than minutes, the user can efficiently create and refine the treatment plans in one sweep instead of opening a second case or going on a break during computations. This is a huge improvement for the clinics that I believe ultimately will lead to better treatment plans as the clinicians will be able to test more options to further tweak the treatments for higher quality”, says Johan Löf, CEO of RaySearch.
RayStation® integrates all RaySearch’s advanced treatment planning solutions into a flexible treatment planning system. It combines unique features such as multi-criteria optimization tools with full support for 4D Adaptive Radiation Therapy. It also includes functionality such as RaySearch’s market-leading algorithms for IMRT and VMAT optimization and highly accurate dose engines for photon, electron and proton therapy. The system is built on the latest software architecture and has a graphical user interface offering state-of-the-art usability.
RaySearch Laboratories is a medical technology company that develops advanced software solutions for improved radiation therapy of cancer. RaySearch provides the RayStation® treatment planning system to clinics all over the world. In addition, RaySearch’s products are distributed through licensing agreements with leading partners such as Philips, Nucletron, IBA, Varian and Brainlab. To date, 15 products have been launched via partners and RaySearch’s software is used by over 2,500 clinics in more than 65 countries. RaySearch was founded in 2000 as a spin-off from the Karolinska Institute in Stockholm and the company is listed in the Small Cap segment on NASDAQ OMX Stockholm.
Source: RaySearch Laboratories
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