Healthcare Industry News: myelodysplastic syndromes
News Release - August 11, 2015
Rich Pharmaceuticals, Inc. Appoints Richard Salvador, Ph.D., Research & Development Expert, To Board of DirectorsBEVERLY HILLS, Calif., Aug. 11, 2015 -- (Healthcare Sales & Marketing Network) -- Rich Pharmaceuticals, Inc. (RCHAE) ("Rich Pharmaceuticals" or the "Company") announced today that Dr. Richard A. Salvador will be joining the corporate board. Dr. Salvador brings over 40 years of biotechnology experience to Rich Pharmaceuticals.
Dr. Salvador has worked the gamut of biotechnology companies from start-ups to major global pharmaceutical companies. Currently, Dr. Salvador is the Chairman of the Board and Founder of Angiogenex and serves on the board of several other biotech companies. While at Hoffman La Roche, Dr. Salvador was Vice President of International Preclinical Development and Deputy to the President of International Research and Development. Dr. Salvador has been actively involved in the governing committees that engaged in all aspects of drug discovery and development processes that led to the successful regulatory approvals and commercialization of numerous drugs at Roche. Additionally, Dr. Salvador has been published in over 50 peer-reviewed journals spanning multiple disease states. He received his Ph.D. Pharmacology, from George Washington University, his A.M. Pharmacology, University School of Medicine, Boston, MA and his Bachelors of Science in Chemistry-Biology from Siena College.
"We are excited to have Dr. Salvador join Rich Pharmaceuticals' board and look forward to utilizing his experience in clinical development and extensive expertise working with the FDA in obtaining approval for drugs," stated Mr. Ben Chang, CEO of Rich Pharmaceuticals. "Our focus is now geared toward finalizing the optimum clinical study protocol for AML with the FDA and continuing to identify clinical trial sites in the United States and Worldwide."
Rich Pharmaceuticals is a clinical-stage biotechnology company focused on developing innovative therapies in oncology, with initial concentration in treating Acute Myelocytic Leukemia (AML), myelodysplastic syndromes (MDS) and Hodgkin's Lymphoma. The lead "platform drug" (RP-323) is a phorbol ester, which induces differentiation and/or apoptosis in multiple cell lines and primary cells, activates protein kinase C (PKC), and modulates the activity of multiple downstream cell signaling pathways, including mitogen-activated protein kinase (MAPK) pathways. TPA induces PKC to produce NF kappa, which produces NF kappa B that has the ability to regulate cellular responses by entering into the nucleus of cell. NF kappa B binds to DNA and changes the nature of the cell and (1) induces differentiation; (2) induces proliferation; (3) cytokine induction; (4) and/or apoptosis.
Acute myelocytic leukemia (AML), also known as acute myelogenous leukemia, is the most common acute leukemia type that affects adults.
AML is an aggressive form of cancer of the blood and the bone marrow, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal white blood cells. In the U.S., about 18,000 new cases of AML are diagnosed annually.
Myelodysplastic Syndrome (MDS) occurs when the blood-forming cells in the bone marrow are damaged which leads to low numbers of one or more types of blood cells. In MDS, some of the cells in the bone marrow are damaged and have problems making new blood cells. Many of the blood cells that are made by these damaged cells are not normal. The abnormal blood cells die sooner than normal cells, leaving the person without enough normal blood cells and with low blood counts. MDS can turn into a fast-growing cancer of bone marrow cells called acute myeloid leukemia and occurs in about 1 out of 3 people with MDS.
Hodgkin's lymphoma is a cancer that is found most frequently in two different age groups: 15 – 35 and over 55, and occurs in both sexes although it is more common in males and individuals with HIV. Malignant Reed Sternberg cells invade and destroy the architecture of the lymph nodes and infiltrate major organs such as the liver and spleen. Radiation and chemotherapy are used routinely but these treatments can later result in morbidity and mortality as a result of causing second malignancies. In the U.S., over 100,000 people suffer from Hodgkin's lymphoma.
About Rich Pharmaceuticals:
Rich Pharmaceuticals, Inc. (RCHA) is a biopharmaceutical company developing a treatment for Acute Myelocytic Leukemia (AML)/white blood cell elevation, myelodysplastic syndromes (MDS), Hodgkin's Lymphoma and other blood related diseases. Rich Pharmaceuticals' goal is to extend refractory patients life expectancy and increase quality of life. Rich Pharmaceuticals' primary development stage product candidate, RP-323, is being designed to treat blood and cancer related diseases through non-evasive outpatient facilities. Find out more at www.richpharmaceuticals.com.
For more information about AML see for example:
For more information about MDS see for example:
For more information about Hodgkin's Lymphoma see for example:
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This news release contains "forward-looking statements" as that term is defined in Section 27(a) of the Securities Act of 1933, as amended, and Section 21(e) of the Securities Exchange Act of 1934, as amended. Statements in this press release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations or intentions regarding the future. Such forward-looking statements include, among other things, references to novel technologies and methods, our business and product development plans, our financial projections or market information. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, the inherent uncertainties associated with developing new products or technologies and operating as a development stage company, our ability to raise the additional funding we will need to continue to pursue our business and product development plans, our ability to develop and commercialize products based on our technology platform, competition in the industry in which we operate and market conditions. These forward-looking statements are made as of the date of this news release, and we assume no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements. Although we believe that any beliefs, plans, expectations and intentions contained in this press release are reasonable, there can be no assurance that any such beliefs, plans, expectations or intentions will prove to be accurate. Investors should consult all of the information set forth herein and should also refer to the risk factors disclosure outlined in the reports and other documents we file with the SEC, available at www.sec.gov.
Source: Rich Pharmaceuticals
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