Healthcare Industry News:  W.L. Gore 

Devices Drug Delivery Product Launch

 News Release - February 6, 2018

Gore to Debut GORE(TM) ImproJect(TM) Plunger for Sensitive Biologics in Pre-Filled Syringes

NEWARK, Del., Feb. 6, 2018 -- (Healthcare Sales & Marketing Network) -- W.L. Gore & Associates, Inc. ("Gore"), a global materials science company, will introduce its new GORE™ ImproJect™ Plunger at Pharmapack 2018, Europe's dedicated pharmaceutical packaging and drug delivery event. Gore will be in Booth A12 at the exhibition, to be held February 7 and 8, 2018, at the Paris Expo, Porte de Versailles.

Russ Hornung, Business Development for Drug Delivery & Packaging for Gore PharmBIO Products, will present "Silicone-Free Delivery of Sensitive Biologics in Glass Pre-Filled Syringes" on Thursday, February 8, at 3:50 PM, at the Pharmapack Learning Lab. The presentation will focus on a new pre-filled syringe technology that can efficiently deliver sensitive biologics while addressing the challenges of interactions between biologics and delivery systems.

Conventional plungers for pre-filled glass syringes are designed to work with lubricated barrels where silicone often acts as the lubricant between plunger and syringe during drug administration and provides a seal between plunger and syringe. However, silicone has been shown to potentially interact with sensitive biologics possibly leading to particulation and aggregation. Over time, the measurable migration of silicone can also cause changes in break and glide force, which may impact injection performance and affect patient comfort. By eliminating silicone from the barrel and the plunger of a pre-filled syringe, the GORE™ ImproJect™ Plunger may enable today's more challenging sensitive biologics to be administered in a pre-filled syringe, a practice that may not have been an option with traditional siliconized pre-filled syringe systems.

"Instead of working to stabilize the silicone or replace it with another lubricant, Gore has taken the completely new approach of eliminating silicone altogether in both plunger and glass barrel," said John Holcombe, Business Leader for Drug Delivery & Packaging for Gore PharmBIO Products. "We look forward to introducing this technology to our colleagues at Pharmapack and speaking more about the potential benefits it holds for patients, care providers, and pharmaceutical formulation and packaging organizations."

About Gore PharmBIO Products

Our technologies, capabilities, and competencies in fluoropolymer science are focused on satisfying the evolving product, regulatory, and quality needs of pharmaceutical and bioprocessing customers, and medical device manufacturers. GORE™ ImproJect™ Plungers, like all products in the Gore PharmBIO Products portfolio, are tested and manufactured under the stringent Gore PharmBIO quality system. The quality system utilizes the process approach and quality management principles contained in ISO9001:2008 (ISO9001), ISO13485:2003 (ISO13485) and ISO15378:2011 (ISO15378). The quality system also complies with appropriate GMP controls when applicable to customer or product specific requirements.

About Gore

W. L. Gore & Associates is a global materials science company dedicated to transforming industries and improving lives. Founded in 1958, Gore has built a reputation for solving complex technical challenges in the most demanding environments — from revolutionizing the outerwear industry with GORE-TEX® fabric to creating medical devices that improve and save lives to enabling new levels of performance in the aerospace, pharmaceutical and mobile electronics markets, among other industries. The company is also known for its strong, team-oriented culture and continued recognition from the Great Place to Work® Institute. Headquartered in Newark, Del., Gore employs approximately 10,000 Associates and generates annual revenues that exceed $3 billion. For more information visit

Source: W.L. Gore

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