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 News Release - March 7, 2017

Ethicon Launches ENSEAL(R) X1 Large Jaw Tissue Sealer, Establishing Next Generation Of Advanced Bipolar Devices

CINCINNATI, March 7, 2017 -- (Healthcare Sales & Marketing Network) -- Ethicon* is setting a new standard for sealing performance in advanced energy devices with the launch of the ENSEAL® X1 Large Jaw Tissue Sealer, the first in a new generation of ENSEAL® devices. ENSEAL® X1 Large Jaw Tissue Sealer has shown better sealing than LigaSure Impact™ through less bleeding1, less thermal spread2 and better ergonomics3. The device is a demonstration of Ethicon's commitment to improving the surgeon experience and is designed to meet the demands of open procedures such as colectomies and hysterectomies.

The ENSEAL® X1 Large Jaw Tissue Sealer was carefully designed to enhance surgeons' efficiency and comfort and is indicated for use in open general, gynecologic, urologic, thoracic, and vascular procedures by offering better hemostasis, better tissue management, and better ergonomics. With a larger distal electrode surface area4, powered by the Ethicon generator with Adaptive Tissue Technology, the ENSEAL® X1 Large Jaw Tissue Sealer had 88% less bleeding in thick tissue compared to LigaSure Impact™1 and 41% less thermal spread2. An overall better design compared to LigaSure Impact™3 offers separate seal and cut functionally and convenient control placement designed for less hand movement5, and 360° shaft rotation is intended to improve access to targeted tissue.6

"I really like the ergonomics, the weight of the instrument, the ease of closure, and also the ease of advancement of the blade to cut through thick tissue," says James Kondrup**, M.D., Minimally Invasive Gynecologic Surgeon at Lourdes Hospital in Binghamton, NY. "This will allow my team and me to stay more focused on the patient and the procedure at hand. The ENSEAL® X1 Large Jaw will be an excellent addition to our toolbox for performing open and vaginal hysterectomies."

With the addition of ENSEAL® X1 Large Jaw Tissue Sealer, Ethicon provides customers access to the most comprehensive Advanced Energy devices portfolio from a single supplier. The ENSEAL® X1 Large Jaw is compatible with the existing Ethicon GEN11 Generator and can replace other products or provide an alternative to existing Ethicon advanced bipolar devices to deliver greater value for the health system.

"ENSEAL X1 is the latest example of how Ethicon is advancing technology to give surgeons greater control, access, and accuracy during surgical procedures in an effort to improve outcomes for patients," says Michael del Prado, Company Group Chairman, Ethicon.

Ethicon, a proven leader in advanced energy, used in approximately 24 million procedures worldwide7, is dedicated to providing intelligent energy solutions to make measurable clinical and cost-of-care improvements for healthcare providers and patients globally. Our focus is to solve unmet surgical needs through our in-depth knowledge of tissue and energy sciences to help improve patient outcomes. Ethicon offers the most complete advanced energy portfolio for open and laparoscopic procedures with our HARMONIC® ultrasonic and ENSEAL® advanced bipolar portfolios, and is now offering MEGADYNE® core electrosurgical tools as part of our suite of energy products.

About Ethicon

From creating the first sutures, to revolutionizing surgery with minimally invasive procedures, Ethicon, part of the Johnson & Johnson Family of Companies, has made significant contributions to surgery for more than 60 years. Our continuing dedication to Shape the Future of Surgery is built on our commitment to help address the world's most pressing health care issues, and improve and save more lives. Through Ethicon's surgical technologies and solutions including sutures, staplers, energy devices, trocars and hemostats and our commitment to treat serious medical conditions like obesity and cancer worldwide, we deliver innovation to make a life-changing impact. Learn more at, and follow us on Twitter @Ethicon.

* Ethicon represents the products and services of Ethicon, Inc., Ethicon Endo-Surgery, LLC and certain of their affiliates. Ethicon Endo-Surgery, Inc. is the legal manufacturer of ENSEAL® and HARMONIC®. All other trademarks are the property of their respective owners.

**Dr. Kondrup is a paid consultant for Ethicon.

1. Preclinical test of distal tip bleeding (ENSEAL® vs Impact-LF4318) in thick porcine mesentery base (p<0.001). (C2169).

2. Preclinical testing on porcine carotids (ENSEAL® vs Impact-LF4318) that measured mean max lateral thermal damage via histology (p=0.005). (C2155)

3. (C2114).

4. (C2166).

5. (C2160).

6. (C2158).

7. *Internal global sales data as of June 2016. (EOS #062951-161108 Claims Central #2197 (replaces C1500)

Source: Ethicon

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